My fuse#18 issue
Thank you all above for the input and things you found. I thought it would be appropriate to share my experience tracking this down on my 2003 Excursion.
Every single time I touched the brakes... *POW*, #18 blew. Started looking for obvious stuff, but nothing.
Disconnected trailer plug etc. via the connector behind the license plate. Tested *POW*
Moved up to the mid-frame area on the drivers side. Disconnected the back end lights from there. *POW* Good thing I have a 20 pack of 20 AMP fuses.
Disconnected those same cables from under the hood right in front of the firewall. *POW*
Disconnected the brake switch. Did not blow, but no brake lights of course. Manually jumped pin 4 and 5 of the brake switch connector. Found a schematic online and those are the contacts bridged by the switch on the 20 amp circuit. *POW* on the manual jumper. Something elsewhere...
Pulled all the relays, etc from the two block areas under the hood just in front of the driver. *POW* The issue is getting in a smaller and smaller area.
Pulled the entire fuse block / power distribution block lose under the dash. 4 bolts 10mm heads. Got a good look behind. Saw nothing. Ready to give up. Tried one last fuse (still have 10 or so left)... maybe it was MY last fuse.

Tried the brake, no blow! What?!?
Added relays, etc. back. Tested. *No blow*
Added connectors under hood. *No blow*
Added mid frame connectors. *No blow*
Added connector behind license plate *No blow*
Mounted fuse block / PDB *No blow*
Everything is back together and working. Driven 150+ miles since and it is still working. Not the outcome I exactly wanted as I wonder when (not if) it will pop up again. Hopefully the extra details of the things I did will help someone else down the line with diagnostics.
2003 Excursion 6.0L Limited
2000 Excursion 7.3L Limited
1971 Suburban dead 350 :-(