The reason it turns into a pissing contest is because people get offended or struck the wrong way, and its unavoidable because really the "pros and cons" are what each separate person thinks, not really stated facts, because its hard to judge a "lag scale" or "definite hp increase" or a "EGT scale".. those things aren't relevant to each specific truck across the board...and will sway one persons opinion greatly from anthers....
so all you're going to get is the discussion that turns into a pissing contest. Some people have known non vgt all their life, some people have only known a tuned 6.4 on stock turbos.
Things are going to vary greatly.
My best advice is to consider the level of fuel your truck is pushing, ask people their setups (specifically... Like saying What is your single setup, Turbo sizing, stall converter, fuel mods, air mods, info pertaining to that only..keeping out the opinionated info) and then take your best informed guess and go with what you think is going to work for you. Really its not that hard for me to figure out what'll work... Cast wheels spool worse, billet and fmw wheels will allow you to go a little larger without added lag, Stock fuel only pushes a single so fast, So you're not gonna run a 475 lol, and yada yada... rant over.